abstract：BACKGROUND AND OBJECTIVE:In Duchenne Muscular Dystrophy (DMD) treatment, muscle fiber size can be considered as an indicator of muscle health and function. In particular, the statistical distribution of fibers cross-sectional areas (CSAs) has been used as quantitative efficacy endpoint. For each patient, assessment of ...

journal_title：Computer methods and programs in biomedicine

authors： Lavezzi SM,Rocchetti M,Bettica P,Petrini S,De Nicolao G

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:The breast dense tissue percentage on digital mammograms is one of the most commonly used markers for breast cancer risk estimation. Geometric features of dense tissue over the breast and the presence of texture structures contained in sliding windows that scan the mammograms may improve the predictive abili...

journal_title：Computer methods and programs in biomedicine

authors： Pérez-Benito FJ,Signol F,Pérez-Cortés JC,Pollán M,Pérez-Gómez B,Salas-Trejo D,Casals M,Martínez I,LLobet R

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Gene regulatory networks (GRNs) are essential for understanding most molecular processes. In this context, the so-called model-free approaches have an advantage modeling the complex topologies behind these dynamic molecular networks, since most GRNs are difficult to map correctly by any other m...

journal_title：Computer methods and programs in biomedicine

authors： Díaz-Montaña JJ,Díaz-Díaz N,Barranco CD,Ponzoni I

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:We propose an automatic approach for fast vertebral body segmentation in three-dimensional magnetic resonance images of the whole spine. Previous works are limited to the lower thoracolumbar section and often take minutes to compute, which is problematic in clinical routine, for study data sets...

journal_title：Computer methods and programs in biomedicine

authors： Rak M,Steffen J,Meyer A,Hansen C,Tönnies KD

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Assessing prognosis for acetaminophen-induced acute liver failure (APAP-ALF) patients during the first week of hospitalization often presents significant challenges. Current models such as the King's College Criteria (KCC) and the Acute Liver Failure Study Group (ALFSG) Prognostic Index are develop...

journal_title：Computer methods and programs in biomedicine

authors： Speiser JL,Karvellas CJ,Wolf BJ,Chung D,Koch DG,Durkalski VL

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In the last decade, RNA-sequencing technology has become method-of-choice and prefered to microarray technology for gene expression based classification and differential expression analysis since it produces less noisy data. Although there are many algorithms proposed for microarray data, the n...

journal_title：Computer methods and programs in biomedicine

authors： Goksuluk D,Zararsiz G,Korkmaz S,Eldem V,Zararsiz GE,Ozcetin E,Ozturk A,Karaagaoglu AE

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:For diagnosis of arrhythmic heart problems, electrocardiogram (ECG) signals should be recorded and monitored. The long-term signal records obtained are analyzed by expert cardiologists. Devices such as the Holter monitor have limited hardware capabilities. For improved diagnostic capacity, it w...

journal_title：Computer methods and programs in biomedicine

authors： Yildirim O,Baloglu UB,Tan RS,Ciaccio EJ,Acharya UR

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Fraction of Inspired Oxygen is one of the arbitrary set ventilator parameters which has critical influence on the concentration of blood oxygen. Normally mechanical ventilators providing respiratory assistance are tuned manually to supply required inspired oxygen to keep the oxygen saturation a...

journal_title：Computer methods and programs in biomedicine

authors： Radhakrishnan S,Nair SG,Isaac J

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Hedyotis diffusa is an herb used for anti-cancer, anti-oxidant, anti-inflammatory, and anti-fibroblast treatment in the clinical practice of Traditional Chinese Medicine. However, its pharmacological mechanisms have not been fully established and there is a lack of modern scientific verificatio...

journal_title：Computer methods and programs in biomedicine

authors： Hu CJ,He J,Li GZ,Fang PP,Xie JD,Ding YW,Mao YQ,Hu KF

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In recent decades, cancer has become one of the most fatal and destructive diseases which is threatening humans life. Accordingly, different types of cancer treatment are studied with the main aim to have the best treatment with minimum side effects. Anti-angiogenic is a molecular targeted the...

journal_title：Computer methods and programs in biomedicine

authors： Yazdjerdi P,Meskin N,Al-Naemi M,Al Moustafa AE,Kovács L

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In recent years, many attempts have been made to design reliable systems for identifying individuals using biometrics. Electrocardiogram (ECG) biometric is one of the newest methods that not only offers unique characteristics of individuals for human identification, but also the possibility of ...

journal_title：Computer methods and programs in biomedicine

authors： Goshvarpour A,Goshvarpour A

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Model-based glycaemic control protocols have shown promise in neonatal intensive care units (NICUs) for reducing both hyperglycaemia and insulin-therapy driven hypoglycaemia. However, current models for the appearance of glucose from enteral feeding are based on values from adult intensive care cohorts. This...

journal_title：Computer methods and programs in biomedicine

authors： Knopp JL,Signal M,Harris DL,Marics G,Weston P,Harding J,Tóth-Heyn P,Hómlok J,Benyó B,Chase JG

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Prostate segmentation on Magnetic Resonance (MR) imaging is problematic because disease changes the shape and boundaries of the gland and it can be difficult to separate the prostate from surrounding tissues. We propose an automated model that extracts and combines multi-level features in a dee...

journal_title：Computer methods and programs in biomedicine

authors： Yan K,Wang X,Kim J,Khadra M,Fulham M,Feng D

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:This paper proposes a novel approach for automatic left ventricle (LV) quantification using convolutional neural networks (CNN). METHODS:The general framework consists of one CNN for detecting the LV, and another for tissue classification. Also, three new deep learning architectures were proposed for LV quan...

journal_title：Computer methods and programs in biomedicine

authors： Curiale AH,Colavecchia FD,Mato G

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Univariate feature selection is one of the simplest and most commonly used techniques to develop a multigene predictor for survival. Presently, there is no software tailored to perform univariate feature selection and predictor construction. METHODS:We develop the compound.Cox R package that i...

journal_title：Computer methods and programs in biomedicine

authors： Emura T,Matsui S,Chen HY

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Brain-Computer Interfaces (BCIs) based on auditory selective attention have been receiving much attention because i) they are useful for completely paralyzed users since they do not require muscular effort or gaze and ii) focusing attention is a natural human ability. Several techniques - such ...

journal_title：Computer methods and programs in biomedicine

authors： de Souza AP,Soares QB,Felix LB,Mendes EMAM

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Detection and classification of pulmonary nodules are critical tasks in medical image analysis. The Lung Image Database Consortium (LIDC) database is a widely used resource for small pulmonary nodule classification research. This dataset is comprised of nodule characteristic evaluations and CT...

journal_title：Computer methods and programs in biomedicine

authors： Kaya A

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There is a huge amount of rare diseases, many of which have associated important disabilities. It is paramount to know in advance the evolution of the disease in order to limit and prevent the appearance of disabilities and to prepare the patient to manage the future difficulties. Rare disease ...

journal_title：Computer methods and programs in biomedicine

authors： Fabregat H,Araujo L,Martinez-Romo J

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Liver quality evaluation is one of the vital steps for predicting the success of liver transplantation. Current evaluation methods, such as biopsy and visual inspection, which are either invasive or lack of consistent standards, provide limited predictive value of long-term transplant viability...

journal_title：Computer methods and programs in biomedicine

authors： Lan Q,Sun H,Robertson J,Deng X,Jin R

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Drug-target interaction prediction plays an intrinsic role in the drug discovery process. Prediction of novel drugs and targets helps in identifying optimal drug therapies for various stringent diseases. Computational prediction of drug-target interactions can help to identify potential drug-ta...

journal_title：Computer methods and programs in biomedicine

authors： Sharma A,Rani R

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This paper presents an improved scheme able to perform accurate segmentation and classification of cancer nuclei in immunohistochemical (IHC) breast tissue images in order to provide quantitative evaluation of estrogen or progesterone (ER/PR) receptor status that will assist pathologists in can...

journal_title：Computer methods and programs in biomedicine

authors： Mouelhi A,Rmili H,Ali JB,Sayadi M,Doghri R,Mrad K

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Congenital anomalies are seen at 1-3% of the population, probabilities of which are tried to be found out primarily through double, triple and quad tests during pregnancy. Also, ultrasonographical evaluations of fetuses enhance detecting and defining these abnormalities. About 60-70% of the ano...

journal_title：Computer methods and programs in biomedicine

authors： Akbulut A,Ertugrul E,Topcu V

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Accurate, reliable, efficient, and precise measurements of the lumen geometry of the common carotid artery (CCA) are important for (a) managing the progression/regression of atherosclerotic build-up and (b) the risk of stroke. The image-based degree of stenosis in the carotid artery and the pla...

journal_title：Computer methods and programs in biomedicine

authors： Kumar PK,Araki T,Rajan J,Laird JR,Nicolaides A,Suri JS,Fellow AIMBE.

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The detection of optic nerve head (ONH) in retinal fundus images plays a key role in identifying Diabetic Retinopathy (DR) as well as other abnormal conditions in eye examinations. This paper presents a method and its associated software towards the development of an Android smartphone app base...

journal_title：Computer methods and programs in biomedicine

authors： Elloumi Y,Akil M,Kehtarnavaz N

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Virtual simulations recreate scenarios where student nurses can practice procedures in a safe and supervised manner and with no risk to the patient. Virtual scenarios include digital characters that reproduce human actions. Generally, these characters are modeled as males and restricted roles a...

journal_title：Computer methods and programs in biomedicine

authors： Boada I,Rodriguez-Benitez A,Thió-Henestrosa S,Olivet J,Soler J

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In the last decade, Ultrasound-Guided Regional Anesthesia (UGRA) gained importance in surgical procedures and pain management, due to its ability to perform target delivery of local anesthetics under direct sonographic visualization. However, practicing UGRA can be challenging, since it require...

journal_title：Computer methods and programs in biomedicine

authors： Alkhatib M,Hafiane A,Tahri O,Vieyres P,Delbos A

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Early diagnosis of cardiac autonomic neuropathy (CAN) is critical for reversing or decreasing its progression and prevent complications. Diagnostic accuracy or precision is one of the core requirements of CAN detection. As the standard Ewing battery tests suffer from a number of shortcomings, r...

journal_title：Computer methods and programs in biomedicine

authors： Abawajy J,Kelarev A,Yi X,Jelinek HF

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Although analytical models have been used to quickly predict head response under impact condition, the existing models generally took the head as regular shell with uniform thickness which cannot account for the actual head geometry with varied cranial thickness and curvature at different locat...

journal_title：Computer methods and programs in biomedicine

authors： Li Z,Ji C,Wang L

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Several studies have evaluated the reproducibility of the Cobb angle for measuring the degree of scoliotic deformities from X-ray spine images, and proposed different geometric models for describing the spinal curvature. The ellipse was shown to be an adequate geometric form, but was not yet ap...

journal_title：Computer methods and programs in biomedicine

authors： Pinheiro AP,Coelho JC,Veiga ACP,Vrtovec T

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Early detection of cardiovascular (CV) disease or associated risk factors during childhood is of paramount importance, allowing for early treatment or lifestyle modifications, respectively. The objective of this study was to describe the development of an electronic health record (EHR), with in...

journal_title：Computer methods and programs in biomedicine

authors： Chatzakis I,Vassilakis K,Lionis C,Germanakis I

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The use of objective detection techniques applied to the auditory steady-state responses (ASSRs) for the assessment of auditory thresholds has been investigated over the years. The idea consists in setting up the audiometric profile without subjective inference from patients and evaluators. The...

journal_title：Computer methods and programs in biomedicine

authors： Silva GM,Antunes F,Henrique CS,Felix LB

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Objective Structured Clinical Examination (OSCE) has been used in many areas of healthcare training over the years. However, it constantly needs to be upgraded and enhanced due to technological and teaching changes. We aim at implementing an integrative OSCE method which employs informatics via...

journal_title：Computer methods and programs in biomedicine

authors： Lin CW,Chang EH,Clinciu DL,Peng YT,Huang WC,Wu CC,Wu JC,Li YC

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The traditional biomedical image retrieval methods as well as content-based image retrieval (CBIR) methods originally designed for non-biomedical images either only consider using pixel and low-level features to describe an image or use deep features to describe images but still leave a lot of...

journal_title：Computer methods and programs in biomedicine

authors： Pang S,Orgun MA,Yu Z

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Complementary and alternative medicine techniques have shown their potential for the treatment and diagnosis of chronical diseases like diabetes, arthritis etc. On the same time digital image processing techniques for disease diagnosis is reliable and fastest growing field in biomedical. Propos...

journal_title：Computer methods and programs in biomedicine

authors： Samant P,Agarwal R

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Respiratory mechanics estimation can be used to guide mechanical ventilation (MV) but is severely compromised when asynchronous breathing occurs. In addition, asynchrony during MV is often not monitored and little is known about the impact or magnitude of asynchronous breathing towards recovery...

journal_title：Computer methods and programs in biomedicine

authors： Chiew YS,Tan CP,Chase JG,Chiew YW,Desaive T,Ralib AM,Mat Nor MB

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In this study, a wireless blood pressure holter that can be used with smart mobile devices was developed. The developed blood pressure holter consists of two parts, which are a smart mobile device and a cuff. The smart mobile device is used as a recording, control and display device through a d...

journal_title：Computer methods and programs in biomedicine

authors： İlhan İ

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The application of medical knowledge strongly affects the performance of intelligent diagnosis, and method of learning the weights of medical knowledge plays a substantial role in probabilistic graphical models (PGMs). The purpose of this study is to investigate a discriminative weight-learning...

journal_title：Computer methods and programs in biomedicine

authors： Jiang J,Xie J,Zhao C,Su J,Guan Y,Yu Q

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:3D freehand Ultrasonography is a medical imaging technique that can be used to measure muscle and tendon morphological and structural properties, including volume, lengths and echo-intensity. These properties are clinically relevant in neurological disorders such as spastic cerebral palsy to mo...

journal_title：Computer methods and programs in biomedicine

authors： Cenni F,Schless SH,Bar-On L,Aertbeliën E,Bruyninckx H,Hanssen B,Desloovere K

更新日期：2018-03-01 00:00:00

abstract：:Interstitial fibrosis in renal biopsy samples is a scarring tissue structure that may be visually quantified by pathologists as an indicator to the presence and extent of chronic kidney disease. The standard method of quantification by visual evaluation presents reproducibility issues in the diagnoses. This study prop...

journal_title：Computer methods and programs in biomedicine

authors： Tey WK,Kuang YC,Ooi MP,Khoo JJ

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Breast cancer is the most common cancer affecting females worldwide. Breast cancer survivability prediction is challenging and a complex research task. Existing approaches engage statistical methods or supervised machine learning to assess/predict the survival prospects of patients. OBJECTIVE:The main objec...

journal_title：Computer methods and programs in biomedicine

authors： Shukla N,Hagenbuchner M,Win KT,Yang J

更新日期：2018-03-01 00:00:00